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Determining the functional relationship between epigenetic and physical chromatin domains in Drosophila

Sandrine Denaud, Gonzalo Sabarís, Marco Di Stefano, Giorgio-Lucio Papadopoulos, Bernd Schuettengruber, Giacomo Cavalli

Integrative single-cell chromatin and transcriptome analysis of human plasma cell differentiation

Elina Alaterre, Sara Ovejero, Caroline Bret, Laure Dutrieux, Dassou Sika, Raul Fernandez Perez, Marion Espéli, Thierry Fest, Michel Cogné, José Ignacio Martin-Subero, Pierre Milpied, Giacomo Cavalli, Jérôme Moreaux

Phase separation and inheritance of repressive chromatin domains

Nazli Akilli, Thierry Cheutin, Giacomo Cavalli

Sustained inactivation of the Polycomb PRC1 complex induces DNA repair defects and genomic instability in epigenetic tumors

Chetan C. Rawal, Vincent Loubiere, Nadejda L. Butova, Juliette Gracia, Victoria Parreno, Chiara Merigliano, Anne-Marie Martinez, Giacomo Cavalli, Irene Chiolo

The mechanistic basis of genetic assimilation in natural fly populations

Giacomo Cavalli, Gonzalo Sabarís, Bernd Schuettengruber, Giorgio L. Papadopoulos, Marta Coronado-Zamora, Maximilian H. Fitz-James, Josefa González

Transient loss of Polycomb components induces an epigenetic cancer fate

V. Parreno, V. Loubiere, B. Schuettengruber, L. Fritsch, C. C. Rawal, M. Erokhin, B. Győrffy, D. Normanno, M. Di Stefano, J. Moreaux, N. L. Butova, I. Chiolo, D. Chetverina, A. M. Martinez, G. Cavalli

The Density of Regulatory Information Is a Major Determinant of Evolutionary Constraint on Noncoding DNA in Drosophila

Gonzalo Sabarís, Daniela M Ortíz, Ian Laiker, Ignacio Mayansky, Sujay Naik, Giacomo Cavalli, David L Stern, Ella Preger-Ben Noon, Nicolás Frankel

PRE loops constitute a topological chromatin structure that restricts and specifies enhancer promoter communication

Giacomo Cavalli, Sandrine Denaud, Marion Bardou, Giorgio-Lucio Papadopoulos, Stefan Grob, Marco Di Stefano, Marcelo Nollmann, Bernd Schuettengruber

EZH2 targeting induces CD38 upregulation and response to anti-CD38 immunotherapies in multiple myeloma

Djamila Chemlal, Emmanuel Varlet, Amelie Machura, Sara Ovejero, Guilhem Requirand, Nicolas Robert, Guillaume Cartron, Elina Alaterre, Caroline Bret, Laure Vincent, Charles Herbaux, Giacomo Cavalli, Angélique Bruyer, Hugues De Boussac, Jerome Moreaux

Interchromosomal contacts between regulatory regions trigger stable transgenerational epigenetic inheritance in Drosophila

Maximilian H. Fitz-James, Gonzalo Sabarís, Peter Sarkies, Frédéric Bantignies, Giacomo Cavalli