Publications

Sandrine Denaud, Gonzalo Sabarís, Marco Di Stefano, Giorgio-Lucio Papadopoulos, Bernd Schuettengruber, Giacomo Cavalli (2025). Determining the functional relationship between epigenetic and physical chromatin domains in Drosophila. Genome Biology.

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Flora Paldi, Giacomo Cavalli (2025). 3D genome folding in epigenetic regulation and cellular memory. Trends in Cell Biology.

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Gonzalo Sabarís, Bernd Schuettengruber, Giorgio L. Papadopoulos, Marta Coronado-Zamora, Maximilian H. Fitz-James, Josefa González, Giacomo Cavalli (2025). A mechanistic basis for genetic assimilation in natural fly populations. Proceedings of the National Academy of Sciences.

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Maximilian H. Fitz-James, Gonzalo Sabarís, Peter Sarkies, Frédéric Bantignies, Giacomo Cavalli (2025). Interchromosomal contacts between regulatory regions trigger stable transgenerational epigenetic inheritance in Drosophila. Molecular Cell.

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Anne-Marie Martinez, Giacomo Cavalli (2025). A possible role for epigenetics in cancer initiation. Comptes Rendus. Biologies.

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Hadrien Reboul, Davide Normanno, Quentin Szabo, Ivana Jerković, Giacomo Cavalli, Frédéric Bantignies (2025). Oligopaint FISH to Study Chromosomal Architecture and Structural Variations. Chromoanagenesis.

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Michael-Florian Szalay, Blanka Majchrzycka, Ivana Jerković, Giacomo Cavalli, Daniel M. Ibrahim (2024). Evolution and function of chromatin domains across the tree of life. Nature Structural & Molecular Biology.

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Flora Paldi, Michael F Szalay, Marco Di Stefano, Daniel Jost, Hadrien Reboul, Giacomo Cavalli (2024). Transient histone deacetylase inhibition induces cellular memory of gene expression and three-dimensional genome folding. bioRxiv.

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Elina Alaterre, Sara Ovejero, Caroline Bret, Laure Dutrieux, Dassou Sika, Raul Fernandez Perez, Marion Espéli, Thierry Fest, Michel Cogné, José Ignacio Martin-Subero, Pierre Milpied, Giacomo Cavalli, Jérôme Moreaux (2024). Integrative single-cell chromatin and transcriptome analysis of human plasma cell differentiation. Blood.

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Sandrine Denaud, Marion Bardou, Giorgio-Lucio Papadopoulos, Stefan Grob, Marco Di Stefano, Gonzalo Sabarís, Marcelo Nollmann, Bernd Schuettengruber, Giacomo Cavalli (2024). A PRE loop at the dac locus acts as a topological chromatin structure that restricts and specifies enhancer–promoter communication. Nature Structural & Molecular Biology.

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Chetan C. Rawal, Vincent Loubiere, Nadejda L. Butova, Juliette Gracia, Victoria Parreno, Chiara Merigliano, Anne-Marie Martinez, Giacomo Cavalli, Irene Chiolo (2024). Sustained inactivation of the Polycomb PRC1 complex induces DNA repair defects and genomic instability in epigenetic tumors. Histochemistry and Cell Biology.

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Nazli Akilli, Thierry Cheutin, Giacomo Cavalli (2024). Phase separation and inheritance of repressive chromatin domains. Current Opinion in Genetics & Development.

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Giacomo Cavalli, Gonzalo Sabarís, Bernd Schuettengruber, Giorgio L. Papadopoulos, Marta Coronado-Zamora, Maximilian H. Fitz-James, Josefa González (2024). The mechanistic basis of genetic assimilation in natural fly populations. Springer Science and Business Media LLC.

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Orli Snir, Michael Elgart, Yulia Gnainsky, Moshe Goldsmith, Filippo Ciabrelli, Shlomi Dagan, Iris Aviezer, Elizabeth Stoops, Giacomo Cavalli, Yoav Soen (2024). Organ transformation by environmental disruption of protein integrity and epigenetic memory in Drosophila. PLOS Biology.

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Guerric Gilbert, Yoan Renaud, Camille Teste, Nadège Anglaret, Romane Bertrand, Sven Hoehn, Tomasz P. Jurkowski, Bernd Schuettengruber, Giacomo Cavalli, Lucas Waltzer, Laurence Vandel (2024). Drosophila TET acts with PRC1 to activate gene expression independently of its catalytic activity. Science Advances.

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Ivana Jerković, Marco Di Stefano, Hadrien Reboul, Michael F Szalay, Davide Normanno, Giorgio L Papadopoulos, Frédéric Bantignies, Giacomo Cavalli (2024). A Scaffolding Element Rewires Local 3D Chromatin Architecture During Differentiation. bioRxiv.

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Victoria Parreno, Vincent Loubiere, Bernd Schuettengruber, Lauriane Fritsch, Chetan C. Rawal, Maxim Erokhin, Balázs Győrffy, Davide Normanno, Marco Di Stefano, Jérôme Moreaux, Nadejda L. Butova, Irene Chiolo, Darya Chetverina, Anne-Marie Martinez, Giacomo Cavalli (2024). Transient loss of Polycomb components induces an epigenetic cancer fate. Nature.

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V. Parreno, V. Loubiere, B. Schuettengruber, L. Fritsch, C. C. Rawal, M. Erokhin, B. Győrffy, D. Normanno, M. Di Stefano, J. Moreaux, N. L. Butova, I. Chiolo, D. Chetverina, A. M. Martinez, G. Cavalli (2024). Transient loss of Polycomb components induces an epigenetic cancer fate. Nature.

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Gonzalo Sabarís, Daniela M Ortíz, Ian Laiker, Ignacio Mayansky, Sujay Naik, Giacomo Cavalli, David L Stern, Ella Preger-Ben Noon, Nicolás Frankel (2024). The Density of Regulatory Information Is a Major Determinant of Evolutionary Constraint on Noncoding DNA in Drosophila. Molecular Biology and Evolution.

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Giacomo Cavalli, Sandrine Denaud, Marion Bardou, Giorgio-Lucio Papadopoulos, Stefan Grob, Marco Di Stefano, Marcelo Nollmann, Bernd Schuettengruber (2023). PRE loops constitute a topological chromatin structure that restricts and specifies enhancer promoter communication. Springer Science and Business Media LLC.

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Djamila Chemlal, Emmanuel Varlet, Amelie Machura, Sara Ovejero, Guilhem Requirand, Nicolas Robert, Guillaume Cartron, Elina Alaterre, Caroline Bret, Laure Vincent, Charles Herbaux, Giacomo Cavalli, Angélique Bruyer, Hugues De Boussac, Jerome Moreaux (2023). EZH2 targeting induces CD38 upregulation and response to anti-CD38 immunotherapies in multiple myeloma. Leukemia.

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Gonzalo Sabarís, Daniela M. Ortíz, Ian Laiker, Ignacio Mayansky, Sujay Naik, Giacomo Cavalli, David L. Stern, Ella Preger-Ben Noon, Nicolás Frankel (2023). The density of regulatory information is a major determinant of evolutionary constraint on non-coding DNA inDrosophila. Cold Spring Harbor Laboratory.

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Maximilian H. Fitz-James, Gonzalo Sabarís, Peter Sarkies, Frédéric Bantignies, Giacomo Cavalli (2023). Interchromosomal contacts between regulatory regions trigger stable transgenerational epigenetic inheritance in Drosophila. Cold Spring Harbor Laboratory.

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Tatyana G. Kahn, Mikhail Savitsky, Chikuan Kuong, Caroline Jacquier, Giacomo Cavalli, Jia-Ming Chang, Yuri B. Schwartz (2023). Topological screen identifies hundreds of Cp190- and CTCF-dependent Drosophila chromatin insulator elements. Science Advances.

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Julian Gurgo, Jean-Charles Walter, Jean-Bernard Fiche, Christophe Houbron, Marie Schaeffer, Giacomo Cavalli, Frédéric Bantignies, Marcelo Nollmann (2022). Multiplexed chromatin imaging reveals predominantly pairwise long-range coordination between Drosophila Polycomb genes. Cold Spring Harbor Laboratory.

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Henri-Marc G. Bourbon, Mikhail H. Benetah, Emmanuelle Guillou, Luis Humberto Mojica-Vazquez, Aissette Baanannou, Sandra Bernat-Fabre, Vincent Loubiere, Frédéric Bantignies, Giacomo Cavalli, Muriel Boube (2022). A shared ancient enhancer element differentially regulates the bric-a-brac tandem gene duplicates in the developing Drosophila leg. PLOS Genetics.

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Jia-Ming Chang, Yi-Fu Weng, Wei-Ting Chang, Fu-an Lin, Giacomo Cavalli (2022). HiCmapTools: a tool to access HiC contact maps. BMC Bioinformatics.

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Amandine Barral, Gabrielle Pozo, Lucas Ducrot, Giorgio L. Papadopoulos, Sandrine Sauzet, Andrew J. Oldfield, Giacomo Cavalli, Jérôme Déjardin (2022). SETDB1/NSD-dependent H3K9me3/H3K36me3 dual heterochromatin maintains gene expression profiles by bookmarking poised enhancers. Molecular Cell.

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Maximilian H. Fitz-James, Giacomo Cavalli (2022). Molecular mechanisms of transgenerational epigenetic inheritance. Nature Reviews Genetics.

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Elina Alaterre, Sara Ovejero, Laurie Herviou, Hugues De Boussac, Giorgio L. Papadopoulos, Marta Kulis, Stéphanie Boireau, Nicolas Robert, Guilhem Requirand, Angélique Bruyer, Guillaume Cartron, Laure Vincent, Anne-Marie Martinez, José Ignacio Martin-Subero, Giacomo Cavalli, Jerome Moreaux (2022). Comprehensive characterization of the epigenetic landscape in Multiple Myeloma. Theranostics.

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Maksim Erokhin, Olga Chetverina, Balázs Győrffy, Victor v. Tatarskiy, Vladic Mogila, Alexander A. Shtil, Igor B. Roninson, Jerome Moreaux, Pavel Georgiev, Giacomo Cavalli, Darya Chetverina (2021). Clinical Correlations of Polycomb Repressive Complex 2 in Different Tumor Types. Cancers.

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Ivana Jerkovic´, Giacomo Cavalli (2021). Understanding 3D genome organization by multidisciplinary methods. Nature Reviews Molecular Cell Biology.

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Henri-Marc G. Bourbon, Mikhail H. Benetah, Emmanuelle Guillou, Luis Humberto Mojica-Vazquez, Aissette Baanannou, Sandra Bernat-Fabre, Vincent Loubiere, Frédéric Bantignies, Giacomo Cavalli, Muriel Boube (2021). Tissue-specific versus pleiotropic enhancers within thebric-a-bractandem gene duplicates display differential regulatory activity and evolutionary conservation. Cold Spring Harbor Laboratory.

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Nikolaus Rajewsky, Geneviève Almouzni, Stanislaw A. Gorski, Stein Aerts, Ido Amit, Michela G. Bertero, Christoph Bock, Annelien L. Bredenoord, Giacomo Cavalli, Susanna Chiocca, Hans Clevers, Bart De Strooper, Angelika Eggert, Jan Ellenberg, Xosé M. Fernández, Marek Figlerowicz, Susan M. Gasser, Norbert Hubner, Jørgen Kjems, Jürgen A. Knoblich, Grietje Krabbe, Peter Lichter, Sten Linnarsson, Jean-Christophe Marine, John C. Marioni, Marc A. Marti-Renom, Mihai G. Netea, Dörthe Nickel, Marcelo Nollmann, Halina R. Novak, Helen Parkinson, Stefano Piccolo, Inês Pinheiro, Ana Pombo, Christian Popp, Wolf Reik, Sergio Roman-Roman, Philip Rosenstiel, Joachim L. Schultze, Oliver Stegle, Amos Tanay, Giuseppe Testa, Dimitris Thanos, Fabian J. Theis, Maria-Elena Torres-Padilla, Alfonso Valencia, Céline Vallot, Alexander Van Oudenaarden, Marie Vidal, Thierry Voet (2021). Publisher Correction: LifeTime and improving European healthcare through cell-based interceptive medicine. Nature.

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Quentin Szabo, Axelle Donjon, Ivana Jerković, Giorgio L. Papadopoulos, Thierry Cheutin, Boyan Bonev, Elphège P. Nora, Benoit G. Bruneau, Frédéric Bantignies, Giacomo Cavalli (2020). Regulation of single-cell genome organization into TADs and chromatin nanodomains. Nature Genetics.

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Nikolaus Rajewsky, Geneviève Almouzni, Stanislaw A. Gorski, Stein Aerts, Ido Amit, Michela G. Bertero, Christoph Bock, Annelien L. Bredenoord, Giacomo Cavalli, Susanna Chiocca, Hans Clevers, Angelika Eggert, Jan Ellenberg, Xosé M. Fernández, Marek Figlerowicz, Susan M. Gasser, Norbert Hubner, Jørgen Kjems, Jürgen A. Knoblich, Grietje Krabbe, Peter Lichter, Sten Linnarsson, Jean-Christophe Marine, John C. Marioni, Marc A. Marti-Renom, Mihai G. Netea, Dörthe Nickel, Marcelo Nollmann, Halina R. Novak, Helen Parkinson, Stefano Piccolo, Inês Pinheiro, Ana Pombo, Christian Popp, Wolf Reik, Sergio Roman-Roman, Philip Rosenstiel, Joachim L. Schultze, Oliver Stegle, Amos Tanay, Giuseppe Testa, Dimitris Thanos, Fabian J. Theis, Maria-Elena Torres-Padilla, Alfonso Valencia, Céline Vallot, Marie Vidal, Thierry Voet, Lavinia Alberi, Stephanie Alexander, Theodore Alexandrov, Ernest Arenas, Claudia Bagni, Robert Balderas, Andrea Bandelli, Burkhard Becher, Matthias Becker, Niko Beerenwinkel, Monsef Benkirame, Marc Beyer, Wendy Bickmore, Erik E. A. L. Biessen, Niklas Blomberg, Ingmar Blumcke, Bernd Bodenmiller, Barbara Borroni, Dimitrios T. Boumpas, Thomas Bourgeron, Sarion Bowers, Dries Braeken, Catherine Brooksbank, Nils Brose, Hilgo Bruining, Jo Bury, Nicolo Caporale, Giorgio Cattoretti, Nadia Chabane, Hervé Chneiweiss, Stuart A. Cook, Paolo Curatolo, Marien I. De Jonge, Bart Deplancke, Bart De Strooper, Peter De Witte, Stefanie Dimmeler, Bogdan Draganski, Anna Drews, Costica Dumbrava, Stefan Engelhardt, Thomas Gasser, Evangelos J. Giamarellos-Bourboulis, Caroline Graff, Dominic Grün, Ivo Gut, Oskar Hansson, David C. Henshall, Anna Herland, Peter Heutink, Stephane R. B. Heymans, Holger Heyn, Meritxell Huch, Inge Huitinga, Paulina Jackowiak, Karin R. Jongsma, Laurent Journot, Jan Philipp Junker, Shauna Katz, Jeanne Kehren, Stefan Kempa, Paulus Kirchhof, Christine Klein, Natalia Koralewska, Jan O. Korbel, Malte Kühnemund, Angus I. Lamond, Elsa Lauwers, Isabelle Le Ber, Ville Leinonen, Alejandro Lopez Tobon, Emma Lundberg, Astrid Lunkes, Henrike Maatz, Matthias Mann, Luca Marelli, Vera Matser, Paul M. Matthews, Fatima Mechta-Grigoriou, Radhika Menon, Anne F. Nielsen, Massimiliano Pagani, R. Jeroen Pasterkamp, Asla Pitkänen, Valentin Popescu, Cyril Pottier, Alain Puisieux, Rosa Rademakers, Dory Reiling, Orly Reiner, Daniel Remondini, Craig Ritchie, Jonathan D. Rohrer, Antoine-Emmanuel Saliba, Raquel Sanchez-Valle, Amedeo Santosuosso, Arnold Sauter, Richard A. Scheltema, Philip Scheltens, Herbert B. Schiller, Anja Schneider, Philip Seibler, Kelly Sheehan-Rooney, David Shields, Kristel Sleegers, August B. Smit, Kenneth G. C. Smith, Ilse Smolders, Matthis Synofzik, Wai Long Tam, Sarah Teichmann, Maria Thom, Margherita Y. Turco, Heleen M. M. Van Beusekom, Rik Vandenberghe, Silvie Van Den Hoecke, Ibo Van De Poel, Andre Van Der Ven, Julie Van Der Zee, Jan Van Lunzen, Geert Van Minnebruggen, Alexander Van Oudenaarden, Wim Van Paesschen, John Van Swieten, Remko Van Vught, Matthijs Verhage, Patrik Verstreken, Carlo Emanuele Villa, Jörg Vogel, Christof Von Kalle, Jörn Walter, Sarah Weckhuysen, Wilko Weichert, Louisa Wood, Anette-Gabriele Ziegler, Frauke Zipp And (2020). LifeTime and improving European healthcare through cell-based interceptive medicine. Nature.

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Yuh Chwen G. Lee, Yuki Ogiyama, Nuno M. C. Martins, Brian J. Beliveau, David Acevedo, C. -Ting Wu, Giacomo Cavalli, Gary H. Karpen (2020). Pericentromeric heterochromatin is hierarchically organized and spatially contacts H3K9me2 islands in euchromatin. PLOS Genetics.

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Ivana Jerković, Quentin Szabo, Frédéric Bantignies, Giacomo Cavalli (2020). Higher-Order Chromosomal Structures Mediate Genome Function. Journal of Molecular Biology.

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Vincent Loubiere, Giorgio L. Papadopoulos, Quentin Szabo, Anne-Marie Martinez, Giacomo Cavalli (2020). Widespread activation of developmental gene expression characterized by PRC1-dependent chromatin looping. Science Advances.

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Thierry Cheutin, Giacomo Cavalli (2019). The multiscale effects of polycomb mechanisms on 3D chromatin folding. Critical Reviews in Biochemistry and Molecular Biology.

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Koustav Pal, Mattia Forcato, Daniel Jost, Thomas Sexton, Cédric Vaillant, Elisa Salviato, Emilia Maria Cristina Mazza, Enrico Lugli, Giacomo Cavalli, Francesco Ferrari (2019). Global chromatin conformation differences in the Drosophila dosage compensated chromosome X. Nature Communications.

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Quentin Szabo, Frédéric Bantignies, Giacomo Cavalli (2019). Principles of genome folding into topologically associating domains. Science Advances.

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Andrés M. Cardozo Gizzi, Diego I. Cattoni, Jean-Bernard Fiche, Sergio M. Espinola, Julian Gurgo, Olivier Messina, Christophe Houbron, Yuki Ogiyama, Giorgio L. Papadopoulos, Giacomo Cavalli, Mounia Lagha, Marcelo Nollmann (2019). Microscopy-Based Chromosome Conformation Capture Enables Simultaneous Visualization of Genome Organization and Transcription in Intact Organisms. Molecular Cell.

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Laurie Herviou, Michel Jourdan, Anne-Marie Martinez, Giacomo Cavalli, Jerome Moreaux (2019). EZH2 is overexpressed in transitional preplasmablasts and is involved in human plasma cell differentiation. Leukemia.

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Orli Snir, Michael Elgart, Filippo Ciabrelli, Shlomi Dagan, Iris Aviezer, Elizabeth Stoops, Giacomo Cavalli, Yoav Soen (2018). Waddington Revisited: Organ transformation by environmental disruption of epigenetic memory. Cold Spring Harbor Laboratory.

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Laurie Herviou, Alboukadel Kassambara, Stéphanie Boireau, Nicolas Robert, Guilhem Requirand, Carsten Müller-Tidow, Laure Vincent, Anja Seckinger, Hartmut Goldschmidt, Guillaume Cartron, Dirk Hose, Giacomo Cavalli, Jerome Moreaux (2018). PRC2 targeting is a therapeutic strategy for EZ score defined high-risk multiple myeloma patients and overcome resistance to IMiDs. Clinical Epigenetics.

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Thierry Cheutin, Giacomo Cavalli (2018). Loss of PRC1 induces higher-order opening of Hox loci independently of transcription during Drosophila embryogenesis. Nature Communications.

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Marc A. Marti-Renom, Genevieve Almouzni, Wendy A. Bickmore, Kerstin Bystricky, Giacomo Cavalli, Peter Fraser, Susan M. Gasser, Luca Giorgetti, Edith Heard, Mario Nicodemi, Marcelo Nollmann, Modesto Orozco, Ana Pombo, Maria-Elena Torres-Padilla (2018). Challenges and guidelines toward 4D nucleome data and model standards. Nature Genetics.

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S. Grob, G. Cavalli (2018). Technical Review: A Hitchhiker's Guide to Chromosome Conformation Capture. Methods Mol Biol.

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Q. Szabo, D. Jost, J. M. Chang, D. I. Cattoni, G. L. Papadopoulos, B. Bonev, T. Sexton, J. Gurgo, C. Jacquier, M. Nollmann, F. Bantignies, G. Cavalli (2018). TADs are 3D structural units of higher-order chromosome organization in Drosophila. Sci Adv.

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Y. B. Schwartz, G. Cavalli (2017). Three-Dimensional Genome Organization and Function in Drosophila. Genetics.

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F. Ciabrelli, F. Comoglio, S. Fellous, B. Bonev, M. Ninova, Q. Szabo, A. Xuereb, C. Klopp, A. Aravin, R. Paro, F. Bantignies, G. Cavalli (2017). Stable Polycomb-dependent transgenerational inheritance of chromatin states in Drosophila. Nat Genet.

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D. I. Cattoni, A. M. C. Gizzi, M. Georgieva, M. Di Stefano, A. Valeri, D. Chamousset, C. Houbron, S. Dejardin, J. B. Fiche, I. Gonzalez, J. M. Chang, T. Sexton, M. A. Marti-Renom, F. Bantignies, G. Cavalli, M. Nollmann (2017). Single-cell absolute contact probability detection reveals chromosomes are organized by multiple low-frequency yet specific interactions. Nat Commun.

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B. Schuettengruber, H. M. Bourbon, L. Di Croce, G. Cavalli (2017). Genome Regulation by Polycomb and Trithorax: 70 Years and Counting. Cell.

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T. Schauer, Y. Ghavi-Helm, T. Sexton, C. Albig, C. Regnard, G. Cavalli, E. E. Furlong, P. B. Becker (2017). Chromosome topology guides the Drosophila Dosage Compensation Complex for target gene activation. EMBO Rep.

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Vincent Loubiere, Anna Delest, Aubin Thomas, Boyan Bonev, Bernd Schuettengruber, Satish Sati, Anne-Marie Martinez, Giacomo Cavalli (2016). Coordinate redeployment of PRC1 proteins suppresses tumor formation during Drosophila development. Nature Genetics.

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M. Entrevan, B. Schuettengruber, G. Cavalli (2016). Regulation of Genome Architecture and Function by Polycomb Proteins. Trends Cell Biol.

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Giacomo Cavalli (2016). Regulation of Genome Architecture and Function by Polycomb Proteins. Trends Cell Biol.

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B. Bonev, G. Cavalli (2016). Organization and function of the 3D genome. Nat Rev Genet.

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J. Bousquet, R. Bourret, T. Camuzat, P. Auge, J. Bringer, M. Nogues, O. Jonquet, J. E. De La Coussaye, J. Ankri, M. Cesari, O. Guerin, B. Vellas, H. Blain, S. Arnavielhe, A. Avignon, B. Combe, G. Canovas, C. Daien, G. Dray, A. Dupeyron, C. Jeandel, I. Laffont, D. Laune, C. Marion, E. Pastor, J. Y. Pelissier, B. Galan, J. Reynes, J. C. Reuzeau, A. Bedbrook, S. Granier, P. A. Adnet, M. Amouyal, B. Alomene, P. L. Bernard, C. Berr, D. Caimmi, P. G. Claret, D. J. Costa, J. P. Cristol, P. Fesler, D. Heve, J. Millot-Keurinck, D. Morquin, G. Ninot, M. C. Picot, N. Raffort, F. Roubille, A. Sultan, J. Touchon, V. Attalin, C. Azevedo, M. Badin, K. Bakhti, B. Bardy, M. P. Battesti, X. Bobia, C. Boegner, S. Boichot, H. Y. Bonnin, S. Bouly, C. Boubakri, J. L. Bourrain, G. Bourrel, V. Bouix, V. Bruguiere, S. Cade, W. Camu, V. Carre, G. Cavalli, G. Cayla, R. Chiron, P. Coignard, F. Coroian, P. Costa, J. Cottalorda, B. Coulet, A. L. Coupet, M. C. Courrouy-Michel, P. Courtet, V. Cros, F. Cuisinier, M. Danko, P. Dauenhauer, M. Dauzat, M. David, J. M. Davy, D. Delignieres, P. Demoly, J. Desplan, P. Dujols, G. Dupeyron, O. Engberink, M. Enjalbert, C. Fattal, J. Fernandes, M. Fouletier, P. Fraisse, P. Gabrion, M. Gellerat-Rogier, Others (2016). MACVIA-LR (Fighting Chronic Diseases for Active and Healthy Ageing in Languedoc-Roussillon): A Success Story of the European Innovation Partnership on Active and Healthy Ageing. J Frailty Aging.

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S. Sati, G. Cavalli (2016). Chromosome conformation capture technologies and their impact in understanding genome function. Chromosoma.

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Giacomo Cavalli (2016). Chromosome conformation capture technologies and their impact in understanding genome function. Chromosoma.

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B. Leblanc, I. Comet, F. Bantignies, G. Cavalli (2016). Chromosome Conformation Capture on Chip (4C): Data Processing. Methods Mol Biol.

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Giacomo Cavalli (2015). PRC1 proteins orchestrate three-dimensional genome architecture. Nature Genetics.

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Vuthy Ea, Tom Sexton, Thierry Gostan, Laurie Herviou, Marie-Odile Baudement, Yunzhe Zhang, Soizik Berlivet, Marie-Noëlle Le Lay-Taha, Guy Cathala, Annick Lesne, Jean-Marc Victor, Yuhong Fan, Giacomo Cavalli, Thierry Forné (2015). Distinct polymer physics principles govern chromatin dynamics in mouse and Drosophila topological domains. BMC Genomics.

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T. Sexton, G. Cavalli (2015). The Role of Chromosome Domains in Shaping the Functional Genome. Cell.

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P. Y. Yung, A. Stuetzer, W. Fischle, A. M. Martinez, G. Cavalli (2015). Histone H3 Serine 28 Is Essential for Efficient Polycomb-Mediated Gene Repression in Drosophila. Cell Rep.

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L. Herviou, G. Cavalli, G. Cartron, B. Klein, J. Moreaux (2015). EZH2 in normal hematopoiesis and hematological malignancies. Oncotarget.

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E. Le Goff, C. Martinand-Mari, M. Martin, J. Feuillard, Y. Boublik, N. Godefroy, P. Mangeat, S. Baghdiguian, G. Cavalli (2015). Enhancer of zeste acts as a major developmental regulator of Ciona intestinalis embryogenesis. Biol Open.

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J. Bousquet, J. M. Anto, K. Berkouk, P. Gergen, J. Pinto Antunes, P. Auge, T. Camuzat, J. Bringer, J. Mercier, N. Best, R. Bourret, M. Akdis, S. H. Arshad, A. Bedbrook, C. Berr, A. Bush, G. Cavalli, M. A. Charles, F. Clavel-Chapelon, M. Gillman, D. R. Gold, M. Goldberg, J. W. Holloway, P. Iozzo, S. Jacquemin, C. Jeandel, F. Kauffmann, T. Keil, G. H. Koppelman, S. Krauss-Etschmann, D. Kuh, S. Lehmann, K. C. Lodrup Carlsen, D. Maier, M. Mechali, E. Melen, J. P. Moatti, I. Momas, P. Nerin, D. S. Postma, K. Ritchie, J. M. Robine, B. Samolinski, V. Siroux, P. E. Slagboom, H. A. Smit, J. Sunyer, R. Valenta, P. Van De Perre, J. M. Verdier, M. Vrijheid, M. Wickman, P. Yiallouros, M. Zins (2015). Developmental determinants in non-communicable chronic diseases and ageing. Thorax.

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T. Cheutin, G. Cavalli (2014). Polycomb silencing: from linear chromatin domains to 3D chromosome folding. Curr Opin Genet Dev.

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Thierry Cheutin, Giacomo Cavalli (2014). Polycomb silencing: from linear chromatin domains to 3D chromosome folding. Current opinion in genetics & development.

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Daniel Jost, Pascal Carrivain, Giacomo Cavalli, Cédric Vaillant (2014). Modeling epigenome folding: formation and dynamics of topologically associated chromatin domains. Nucleic acids research.

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Alexey Gavrilov, Sergey v Razin, Giacomo Cavalli (2014). In vivo formaldehyde cross-linking: it is time for black box analysis. Briefings in functional genomics.

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I. Gonzalez, J. Mateos-Langerak, A. Thomas, T. Cheutin, G. Cavalli (2014). Identification of Regulators of the Three-Dimensional Polycomb Organization by a Microscopy-Based Genome-wide RNAi Screen. Mol Cell.

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Inma Gonzalez, Julio Mateos-Langerak, Aubin Thomas, Thierry Cheutin, Giacomo Cavalli (2014). Identification of Regulators of the Three-Dimensional Polycomb Organization by a Microscopy-Based Genome-wide RNAi Screen. Molecular cell.

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Bernd Schuettengruber, Noa Oded Elkayam, Tom Sexton, Marianne Entrevan, Shani Stern, Aubin Thomas, Eitan Yaffe, Hugues Parrinello, Amos Tanay, Giacomo Cavalli (2014). Cooperativity, Specificity, and Evolutionary Stability of Polycomb Targeting in< i> Drosophila</i>. Cell reports.

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G. Cavalli (2014). Chromosomes: now in 3D!. Nat Rev Mol Cell Biol.

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Filippo Ciabrelli, Giacomo Cavalli (2014). Chromatin driven behavior of topologically associating domains. Journal of molecular biology.

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G. Cavalli (2014). A RING to Rule Them All: RING1 as Silencer and Activator. Dev Cell.

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T. Sexton, G. Cavalli (2013). The 3D genome shapes up for pluripotency. Cell Stem Cell.

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B. Schuettengruber, G. Cavalli (2013). Polycomb domain formation depends on short and long distance regulatory cues. PLoS One.

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G. Cavalli, T. Misteli (2013). Functional implications of genome topology. Nat Struct Mol Biol.

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A. Tanay, G. Cavalli (2013). Chromosomal domains: epigenetic contexts and functional implications of genomic compartmentalization. Curr Opin Genet Dev.

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T. Sexton, E. Yaffe, E. Kenigsberg, F. Bantignies, B. Leblanc, M. Hoichman, H. Parrinello, A. Tanay, G. Cavalli (2012). Three-dimensional folding and functional organization principles of the Drosophila genome. Cell.

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A. Delest, T. Sexton, G. Cavalli (2012). Polycomb: a paradigm for genome organization from one to three dimensions. Curr Opin Cell Biol.

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A. Popkova, R. Bernardoni, C. Diebold, V. Van De Bor, B. Schuettengruber, I. González, A. Busturia, G. Cavalli, A. Giangrande (2012). Polycomb controls gliogenesis by regulating the transient expression of the Gcm/Glide fate determinant. PLoS Genet.

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G. Cavalli (2012). Molecular biology. EZH2 goes solo. Science.

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N. Iovino, G. Cavalli (2011). Rolling ES Cells Down the Waddington Landscape with Oct4 and Sox2. Cell.

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F. Bantignies, V. Roure, I. Comet, B. Leblanc, B. Schuettengruber, J. Bonnet, V. Tixier, A. Mas, G. Cavalli (2011). Polycomb-Dependent Regulatory Contacts between Distant Hox Loci in Drosophila. Cell.

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F. Bantignies, G. Cavalli (2011). Polycomb group proteins: repression in 3D. Trends Genet.

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S. Tajbakhsh, G. Cavalli, E. Richet (2011). Integrated gene regulatory circuits: celebrating the 50(th) anniversary of the operon model. Mol Cell.

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G. Cavalli (2011). From linear genes to epigenetic inheritance of three-dimensional epigenomes. Journal of molecular biology.

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M. Hetzer, G. Cavalli (2011). Eukaryotic cells. Curr Opin Cell Biol.

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I. Comet, B. Schuettengruber, T. Sexton, G. Cavalli (2011). A chromatin insulator driving three-dimensional Polycomb response element (PRE) contacts and Polycomb association with the chromatin fiber. Proceedings of the National Academy of Sciences of the United States of America.

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A. M. Martinez, G. Cavalli (2010). Uncovering a tumor-suppressor function for Drosophila polycomb group genes. Cell Cycle.

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T. Cheutin, F. Bantignies, B. Leblanc, G. Cavalli (2010). Chromatin folding: from linear chromosomes to the 4D nucleus. Cold Spring Harb Symp Quant Biol.

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B. Schuettengruber, G. Cavalli (2009). Recruitment of polycomb group complexes and their role in the dynamic regulation of cell fate choice. Development.

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A. M. Martinez, B. Schuettengruber, S. Sakr, A. Janic, C. Gonzalez, G. Cavalli (2009). Polyhomeotic has a tumor suppressor activity mediated by repression of Notch signaling. Nat Genet.

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T. Sexton, F. Bantignies, G. Cavalli (2009). Genomic interactions: chromatin loops and gene meeting points in transcriptional regulation. Semin Cell Dev Biol.

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B. Schuettengruber, M. Ganapathi, B. Leblanc, M. Portoso, R. Jaschek, B. Tolhuis, M. Van Lohuizen, A. Tanay, G. Cavalli (2009). Functional Anatomy of Polycomb and Trithorax Chromatin Landscapes in Drosophila Embryos. PLoS Biol.

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G. Reuter, G. Cavalli (2009). Epigenetics and the control of multicellularity. Workshop on chromatin at the nexus of cell division and differentiation. EMBO Rep.

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J. Mateos-Langerak, G. Cavalli (2008). Polycomb group proteins and long-range gene regulation. Adv Genet.

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B. Schuettengruber, D. Chourrout, M. Vervoort, B. Leblanc, G. Cavalli (2007). Genome Regulation by Polycomb and Trithorax Proteins. Cell.

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C. Lanctot, T. Cheutin, M. Cremer, G. Cavalli, T. Cremer (2007). Dynamic genome architecture in the nuclear space: regulation of gene expression in three dimensions. Nat Rev Genet.

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E. Zuckerkandl, G. Cavalli (2007). Combinatorial epigenetics, \"junk DNA\", and the evolution of complex organisms. Gene.

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G. Cavalli (2007). Chromosome kissing. Curr Opin Genet Dev.

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A. M. Martinez, G. Cavalli (2006). The role of polycomb group proteins in cell cycle regulation during development. Cell Cycle.

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C. Grimaud, F. Bantignies, M. Pal-Bhadra, P. Ghana, U. Bhadra, G. Cavalli (2006). RNAi Components Are Required for Nuclear Clustering of Polycomb Group Response Elements. Cell.

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I. Comet, E. Savitskaya, B. Schuettengruber, N. Negre, S. Lavrov, A. Parshikov, F. Juge, E. Gracheva, P. Georgiev, G. Cavalli (2006). PRE-Mediated Bypass of Two Su(Hw) Insulators Targets PcG Proteins to a Downstream Promoter. Dev Cell.

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A. M. Martinez, S. Colomb, J. Dejardin, F. Bantignies, G. Cavalli (2006). Polycomb group-dependent Cyclin A repression in Drosophila. Genes Dev.

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N. Negre, S. Lavrov, J. Hennetin, M. Bellis, G. Cavalli (2006). Mapping the Distribution of Chromatin Proteins by ChIP on Chip. Methods Enzymol.

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C. Grimaud, N. Negre, G. Cavalli (2006). From genetics to epigenetics: the tale of Polycomb group and trithorax group genes. Chromosome Res.

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N. Negre, J. Hennetin, L. v. Sun, S. Lavrov, M. Bellis, K. P. White, G. Cavalli (2006). Chromosomal Distribution of PcG Proteins during Drosophila Development. PLoS Biol.

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G. Cavalli (2006). Chromatin and epigenetics in development: blending cellular memory with cell fate plasticity. Development.

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F. Bantignies, G. Cavalli (2006). Cellular memory and dynamic regulation of polycomb group proteins. Curr Opin Cell Biol.

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A. Akhtar, G. Cavalli (2005). The epigenome network of excellence. PLoS Biol.

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J. Dejardin, A. Rappailles, O. Cuvier, C. Grimaud, M. Decoville, D. Locker, G. Cavalli (2005). Recruitment of Drosophila Polycomb group proteins to chromatin by DSP1. Nature.

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J. Dejardin, G. Cavalli (2005). Epigenetic inheritance of chromatin states mediated by Polycomb and trithorax group proteins in Drosophila. Prog Mol Subcell Biol.

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J. Dejardin, G. Cavalli (2005). [Recruitment of Drosophila Polycomb group proteins to chromatin by DSP1]. Med Sci (Paris).

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L. Melnikova, F. Juge, N. Gruzdeva, A. Mazur, G. Cavalli, P. Georgiev (2004). Interaction between the GAGA factor and Mod(mdg4) proteins promotes insulator bypass in Drosophila. Proc Natl Acad Sci U S A.

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G. Chanas, S. Lavrov, F. Iral, G. Cavalli, F. Maschat (2004). Engrailed and polyhomeotic maintain posterior cell identity through cubitus-interruptus regulation. Dev Biol.

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A. A. Aravin, M. S. Klenov, V. v. Vagin, F. Bantignies, G. Cavalli, V. A. Gvozdev (2004). Dissection of a natural RNA silencing process in the Drosophila melanogaster germ line. Mol Cell Biol.

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S. Lavrov, J. Déjardin, G. Cavalli (2004). Combined immunostaining and FISH analysis of polytene chromosomes. Methods Mol Biol.

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J. Dejardin, G. Cavalli (2004). Chromatin inheritance upon Zeste-mediated Brahma recruitment at a minimal cellular memory module. Embo J.

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C. B. Zraly, D. R. Marenda, R. Nanchal, G. Cavalli, C. Muchardt, A. K. Dingwall (2003). SNR1 is an essential subunit in a subset of Drosophila brm complexes, targeting specific functions during development. Dev Biol.

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L. v. Sun, L. Chen, F. Greil, N. Nègre, T. R. Li, G. Cavalli, H. Zhao, B. Van Steensel, K. White (2003). Protein-DNA interaction mapping using genomic tiling path microarrays in Drosophila. Proc. Natl. Acad. Sci. USA.

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F. Bantignies, C. Grimaud, S. Lavrov, M. Gabut, G. Cavalli (2003). Inheritance of Polycomb-dependent chromosomal interactions in Drosophila. Genes Dev.

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S. Bloyer, G. Cavalli, H. W. Brock, J. M. Dura (2003). Identification and characterization of polyhomeotic PREs and TREs. Dev Biol.

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A. Grienenberger, B. Miotto, T. Sagnier, G. Cavalli, V. Schramke, V. Geli, M. C. Mariol, H. Berenger, Y. Graba, J. Pradel (2002). The MYST domain acetyltransferase Chameau functions in epigenetic mechanisms of transcriptional repression. Curr Biol.

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G. Cavalli (2002). Chromatin as a eukaryotic template of genetic information. Curr Opin Cell Biol.

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G. Cavalli, V. Orlando, R. Paro (1999). Mapping DNA target sites of chromatin-associated proteins by formaldehyde cross-linking in Drosophila embryos. Chromosome structural analysis: a practical approach.

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G. Cavalli, R. Paro (1999). Epigenetic inheritance of active chromatin after removal of the main transactivator. Science.

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G. Cavalli, R. Paro (1998). The Drosophila Fab-7 chromosomal element conveys epigenetic inheritance during mitosis and meiosis. Cell.

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R. Paro, H. Strutt, G. Cavalli (1998). Heritable chromatin states induced by the Polycomb and trithorax group genes. Novartis Found Symp.

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G. Cavalli, R. Paro (1998). Chromo Domain Proteins: Linking Chromatin Structure to Epigenetic Regulation. Curr. Opin. Cell Biol..

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H. Strutt, G. Cavalli, R. Paro (1997). Co-localization of Polycomb protein and GAGA factor on regulatory elements responsible for the maintenance of homeotic gene expression. Embo J.

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G. Cavalli, D. Bachmann, F. Thoma (1996). Inactivation of topoisomerases affects transcription dependent chromatin transitions in rDNA but not in a gene transcribed by RNA-polymerase II. EMBO J..

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F. Thoma, G. Cavalli, S. Tanaka (1993). Structural and functional organisation of yeast chromatin. The Eukaryotic Genome (eds. Broda, Oliver & Sims). Cambridge Univ. Press..

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G. Cavalli, F. Thoma (1993). Chromatin transitions during activation and repression of galactose-regulated genes in yeast. EMBO J..

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E. Casali, G. Cavalli, A. Spisni, L. Masotti (1992). Effect of Hydroxystearic acid on proliferation of C108 cells from Lewis lung carcinoma. In Recent Advances in Cellular and Molecular Biology. Eds. Wegmann, R., J. and Wegmann, M., A. Peeters Press..

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G. Cavalli, E. Casali, A. Spisni, L. Masotti (1991). Identification of the peroxidation product Hydroxystearic acid in Lewis lung carcinoma cells. Biochem. Biophys. Res. Commun..

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