Welcome to our new Postdoc Marco!
He will be working on the role of epigenetic memory in fly cancer models!
Marco obtained his PhD in Biochemistry at the Instituto de Biotecnología (UNAM, Mexico), where he studied the trithorax-group protein Tonalli A (TnaA), a SUMO E3 ligase that regulates the expression of Hox genes during Drosophila development.
His project in the lab aims at understanding whether transient disruptions of Polycomb-mediated epigenetic memory can trigger brain tumor formation in Drosophila, using approaches such as inhibition of Polycomb function or alteration of Polycomb nuclear condensates. A central goal is to understand how these perturbations promote cancer by destabilizing transcriptional programs and disrupting epigenetic memory.