Cavalli Lab | Chromatin & Epigenetics | IGH CNRS UMR9002, Montpellier
Research
The Cavalli lab aims at understanding epigenetic inheritance, namely the information that is contained in our chromosomes and transmitted to daughter cells and to future generations beyond the sequence of DNA . We employ a wide range of molecular and in vivo approaches — single-cell omics, super-resolution microscopy, CRISPR editing, genomics, and physical modeling — to uncover how the 3D epigenome in general, and Polycomb proteins in particular, can establish and maintains transcriptional programs in development and disease. Our main research topics include:
News
Publications
(2025).
Determining the functional relationship between epigenetic and physical chromatin domains in Drosophila.
Genome Biology.
(2025).
3D genome folding in epigenetic regulation and cellular memory.
Trends in Cell Biology.
(2025).
A mechanistic basis for genetic assimilation in natural fly populations.
Proceedings of the National Academy of Sciences.
(2025).
A possible role for epigenetics in cancer initiation.
Comptes Rendus. Biologies.
Funding
